• have a planned surgery. Your healthcare provider may stop treatment with HYMPAVZI before your surgery. Talk to your healthcare provider about when to stop using HYMPAVZI and when to start it again if you have a planned surgery. 
• have a severe short-term (acute) illness such as an infection or injury. 
• have been told that you have a risk for blood clots. 
• are pregnant or plan to become pregnant. HYMPAVZI may harm your unborn baby.
  
  Females who are able to become pregnant: 
  • Your healthcare provider will do a pregnancy test before you start your treatment with HYMPAVZI. 
  • You should use effective birth control (contraception) during treatment with HYMPAVZI and for at least 2 months after the last dose of HYMPAVZI. 
  • Tell your healthcare provider right away if you become pregnant or think that you may be pregnant during treatment with HYMPAVZI. 
• are breastfeeding or plan to breastfeed. It is not known if HYMPAVZI passes into your breast milk.

• blood clots (thromboembolic events). HYMPAVZI may increase the risk for your blood to clot in blood vessels in your arm, leg, lung, or head which can be life-threatening. Blood clots have happened in people using HYMPAVZI. You may have an increased risk of blood clots if you have certain risk factors. Stop using HYMPAVZI and get medical help right away if you develop any of these signs or symptoms of blood clots: swelling or pain in arms or legs, redness or discoloration in your arms or legs, shortness of breath, pain in chest or upper back, fast heart rate, cough up blood, feel faint, headache, numbness in your face, eye pain or swelling, trouble seeing

• allergic reactions. HYMPAVZI may cause allergic reactions, including rash and itching. Stop using HYMPAVZI and get medical help right away if you develop any of the following symptoms of a severe allergic reaction: swelling of your face, lips, mouth, or tongue, trouble breathing, wheezing, dizziness or fainting, fast heartbeat or pounding in your chest, sweating

00:00

Peter

My name is Peter. I'm 63. I have hemophilia A, severe, and was diagnosed at the age of two.

00:09

Peter

It was pretty rough back at that point because there was no real treatment at all except for whole blood. So, we would drive almost 2 hours to Hamilton, for treatment.

00:20

Peter

And then, I believe, when I was about ten, we finally were able to take the product home with us. When you're doing a factor replacement, you need alcohol wipes, a tourniquet, the whole procedure. You have to mix the product together, as opposed to opening the pen. Nothing to mix. You take it out of the fridge, and it’s done for you.

00:43

Peter

The discussions with my doctor about the products were very to the point. They said that there was a trial, if I'd be interested in it. Fewer injections and it didn't involve intravenous, so that obviously caught my attention quickly.

1:01

Peter

I've been on it for at least a year and it’s very straightforward, and doesn’t consume much of my time.

1:10

Peter

I think the once-a-week dosing is definitely better for me. I chose Sunday nights. I’m sitting on the couch maybe watching the TV or, or some football or something, and it's so much easier for me just to do it at that point.

1:28

Peter

We do like to go away quite often and again it was always packing up a special amount of the product that I would take with me. How much do I have to bring with me?

1:41

Peter

Going away to Europe, three weeks, three pens. It was nice not being tied down with all the other product. The innovations mean I can concentrate on the things that are important to me.

1:56

Peter

What I enjoy about golf is being able to do it physically and just the freedom of clearing your head from other obstacles, and I think that's why everybody does play the game.

2:13

Peter

Everything I've gone through, I think meeting my wife and being with her is the silver lining in my life.

2:21

Peter

She began quilting probably ten years ago and then I would help her cut the fabric; we would work together like that.

2:34

Peter

I know that some people in studies had injection site reactions, headache, and itching, and that thromboembolic events are possible.

2:44

Peter

If somebody is considering HYMPAVZI, definitely talk to your doctor or to your hemophilia clinic. I'm certainly glad that I did.

2:52

Peter

Living with hemophilia I've had some rough patches. I've had some really incredible patches too. I managed to survive and thrive. Not just to exist, but to live, travel, see the world, have a partner.

3:17

Joanna

Is it nice?

3:18

Peter

Beautiful. Turned out very nice.

3:21

Joanna

Yeah, it's a beautiful color combination, right?

3:24

Peter

Ask your doctor about HYMPAVZI, and whether it would be right for you.

3:29

Voiceover

HYMPAVZI is a prescription medicine used regularly to prevent or reduce the frequency of bleeding episodes in adults and children 6 years of age and older with: 

• hemophilia A with or without factor VIII inhibitors, or  
• hemophilia B with or without factor IX inhibitors. 

It is not known if HYMPAVZI is safe and effective in children younger than 6 years of age. 

Important: Before you start using HYMPAVZI, it is very important to talk to your healthcare provider about using factor VIII and factor IX products or “bypassing agents” (products that help blood clot but work in a different way than HYMPAVZI).
Your healthcare provider may prescribe factor VIII or factor IX medicines, or bypassing agents to treat episodes of breakthrough bleeding during your treatment with HYMPAVZI. Carefully follow your healthcare provider’s instructions regarding when to use these medicines and the prescribed dose during your treatment with HYMPAVZI. Do not use additional doses of HYMPAVZI to treat breakthrough bleeds.

Before using HYMPAVZI, tell your healthcare provider about all of your medical conditions, including if you:

• have a planned surgery. Your healthcare provider may stop treatment with HYMPAVZI before your surgery. Talk to your healthcare provider about when to stop using HYMPAVZI and when to start it again if you have a planned surgery. 
• have a severe short-term (acute) illness such as an infection or injury. 
• have been told that you have a risk for blood clots. 
• are pregnant or plan to become pregnant. HYMPAVZI may harm your unborn baby.

Tell your healthcare provider about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.

If you inject too much HYMPAVZI, call your healthcare provider or the Poison Help Line at 1-800-222-1222 or go to the nearest hospital emergency room right away.

• blood clots (thromboembolic events). HYMPAVZI may increase the risk for your blood to clot in blood vessels in your arm, leg, lung, or head, which can be life-threatening. Blood clots have happened in people using HYMPAVZI. You may have an increased risk of blood clots if you have certain risk factors. Stop using HYMPAVZI and get medical help right away if you develop any of these signs or symptoms of blood clots:

• allergic reactions. HYMPAVZI may cause allergic reactions, including rash and itching. Stop using HYMPAVZI and get medical help right away if you develop any of the following symptoms of a severe allergic reaction:

The most common side effects of HYMPAVZI include: